Okami Medical’s LOBO Vascular Occlusion System, US

The vascular occluders LOBO-3, LOBO-5, LOBO-7, and LOBO-9, developed by Okami Medical, are all purpose-built, microcatheter-delivered devices that are used for the quick and complete occlusion of various peripheral blood vessels.

LOBO® vascular occluders are the primary fringe embolisation gadget that is controlled by restrictive HDBRAIDTM innovation, an imaginative plaiting technique for creating vascular impediment gadgets.

In November 2019, the US Food and Drug Administration (FDA) granted the LOBO® vascular occlusion system 510(k) clearance. LOBO-5 vascular occluder, the organization's second contribution in the LOBO® vascular impediment framework portfolio, got the FDA 510(k) freedom in December 2020, while LOBO-7 and LOBO-9 vascular occluders were cleared by the FDA in June 2022.

The LOBO® occluder gadgets furnish interventional doctors with a negligibly obtrusive single clinical gadget answer for the impediment of different blood vessel targets, even in little and distant areas. It helps in the effective conclusion of fringe vessels all through the body for the treatment of various circumstances.

Plan and elements

The LOBO® vascular impediment framework incorporates a licensed plan with HDBRAID™ innovation to shape a profoundly occlusive pore structure that stimulates the vessel conclusion by fundamentally diminishing the blood stream. The Lobo-3 occluder is designed to be utilized in blood vessels with a diameter of 1.5 to 3 millimeters. LOBO-5 is designed to be used in blood vessels with a diameter of 3 to 5 millimeters, whereas LOBO-7 and LOBO-9 can be used in blood vessels with a diameter of 5 to 7 millimeters and 7 to 9 millimeters, respectively.

The three-disc design of the LOBO® occluder increases HDBRAIDTM's occlusive power and enhances its ability to track vessels that are small or twisted. It conforms to curved vessels and expands the accessible anatomical locations.

Compatibility with low-profile 0.027-inch microcatheters, radiopaque marker bands for visualization, full retrievability, and cutting-edge instantaneous mechanical detachment are just a few of the user-friendly features of the LOBO® occlusion system.

How the LOBO vascular occlusion system works An appropriate LOBO® occluder is positioned for deployment during a procedure after being advanced through the delivery catheter into a blood vessel. As soon as the delivery catheter is retracted, the occluder begins to self-expand and securely engages the vessel wall, resulting in a highly stable implant. The flexible occluder adapts to a wide variety of targets, including vessels with extreme curvature.

The LOBO® occluder can be instantly released and the pusher wire retracted by retracting a button on the user-friendly mechanical detachment handpiece attached to it. The system's dense pore structure allows for the rapid expansion of the vessel lumen, which effectively and quickly obstructs blood flow.

The system's non-clinical testing and MRI simulations have shown that the device is MR conditional and that the person with the implant can undergo MRI scanning safely if certain magnetic field conditions are met, such as a maximum spatial gradient magnetic field of 2000 gauss/cm and 1.5T or 3T field strengths.

HDBRAID technology HDBRAIDTM technology is a novel braiding technique with pores that are four times smaller and four times denser than those found in conventional methods. The pore structure accelerates hemostasis and thrombosis by significantly reducing blood flow to a specific location.

It has over 5,000 pores, allowing for quick and long-lasting occlusion with just one device. The innovation permits the framework to be exceptionally steady after situation with no spinnaker impact.

Benefits of the UK Peripheral Vascular Procedures market system The highly occlusive braided structure of the LOBO® vascular system eliminates the need for various embolic devices by allowing vascular occlusions throughout the body and reducing blood flow.

Dissimilar to loops with unpredictable mass and enormous pores, LOBO® vascular impediment framework offers a high-thickness and little pore structure for vessel impediment. It aids in trauma and unstable bleeding and improves procedure stability.